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CFA-induced pain Under temporal anesthesia with 3% isoflurane, the CFA-induced inflammatory pain model was established via the intraplantar injection of 20 L of CFA

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(2009) Diabetes Study in diet-induced obese rats examining AOD 9604 effects on serum leptin levels and hypothalamic leptin receptor signaling

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Preclinical studies suggest GLP-1 agonists may reduce synovial macrophage infiltration and decrease production of matrix metalloproteinasesenzymes responsible for cartilage degradation in RA

Its primary job is to enhance insulin secretion and suppress excessive glucose production in the liver